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To view a copy of this license, visit About this article Cite this article Zhang, D., Li, D., Hu, Y

This defense system thus provides a critical layer of localized protection specifically within this susceptible organelle, offering new insights for understanding cellular resilience and identifying potential therapeutic targets in neurodegenerative disorders where mitochondrial dysfunction is a core pathological feature

iPSC-Derived Tissue Models And Organoid Platforms Traditional two-dimensional cell culture models have significant limitations in simulating the human tissue microenvironment and multicellular interactions

This creates a vicious cycle where stress damages the very brain structures needed to regulate stress

[DOI] [PubMed] [Google Scholar] 635

Treatment of diverse patient meningiomas ex vivo with 8803 induces direct tumor cytotoxicity through inflammatory cell death pathways, including induction of gasdermin D membrane pore formation