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This may be through regulation of the inflammatory mediator TNF- and intercellular adhesion molecule 1 (ICAM-1) expression (Ji et al., 2016)

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Intraperitoneal administration of curcumin (50 mg/kg/day) decreased up to 80% brain tumors in rats with negligible damages observed in tissues (transaminases, creatinine, alkaline phosphatase)

Other types, like hydroxocobalamin, might be used for different reasons

10.1016/j.toxlet.2015.05.001 216 WaseemM.PandeyP.TomarB.RaisuddinS.ParvezS