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Sikiric did not respond to repeated requests to share data from the trial

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Statistical analysis GraphPad Prism 8 software was utilized for data visualization, and the outcomes were presented as means standard deviation (SD)

Statistical Analysis Statistical analysis was performed by parametric one-way analysis of variance (ANOVA), with the NewmanKeuls post hoc test or the non-parametric KruskalWallis test and subsequently the MannWhitney U test to compare groups

Endothelial dysfunction is associated with decreased bioavailability of nitric oxide (NO) due to an increase in ROS, with a similar physiological change seen in cases of decreased GSH pools [16]