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10.1002/aja.1001270402 187 PfeifferT.PollS.BancelinS.AngibaudJ.Krishna InavalliV

acute effects Reduced administration Frequency: Once-weekly research administration protocols feasible Steady-State Pharmacology: Investigation of metabolic adaptations under sustained receptor activation Translational Relevance: Models clinically relevant long-acting formulation pharmacology Protease Stability: Semaglutide carries a DPP-4-resistant Aib8 substitution, while cagrilintide (an amylin analog, not a DPP-4 substrate) is stabilized by lipidation and albumin binding

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Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues