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Indeed, it may be difficult or even impossible to determine whether, in terms of oxidative stress, modern factors such as pharmaceuticals, pollutants from the combustion of fossil fuels, and other factors from industrial processes outweigh more historical factors such as smoke from cooking fires and naturally occurring toxins from food obtained by hunting and gathering

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doi:10.2310/8000.2011.110512 Zulfiqar S, Qureshi A, Dande R, Puri C, Persaud K, Awasthi S