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In rare cases, there may be: arrhythmia

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[DOI] [PubMed] [Google Scholar] 130.Becker D.A.B., Laura J., Galetta S.L

Allergic reactionsmanifesting as hives, itching across multiple body areas, or throat tightnessare rare but demand immediate medical attention

This pathway is responsible for the bodys entire sulfur-based detoxification system

The risk of vitamin B12 deficiency is higher in patients with T2D receiving high metformin doses for an extended period or in the presence of other known risk factors associated with vitamin B12 deficiency, such as advanced age and regular use of acid-suppressing medications