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10.1002/ana.25303 [DOI] [PMC free article] [PubMed] [Google Scholar] Tyuryaeva I., Lyublinskaya O., Tyuryaeva I., Lyublinskaya O

The loss of functionality and adaptability of important biomolecules due to oxidative stress are two interdependent biological processes, which are among the important factors that mediate aging

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The glutathione S-transferase genes code for enzymes involved in the removal of a variety of carcinogens and environmental toxins.[ref] These phase II detoxification enzymes combine the metabolites from phase I with molecules that make them less toxic and more easily excreted