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Katz JN, Arant KR, Loeser RF

Inject subcutaneously 1-2 inches from the wound edge rather than directly into damaged tissue

And SAMe depends on Step 2 the bottleneck where your MTHFR enzyme sits

If weight changes occur, they're more plausibly secondary effectsthrough improved recovery, training consistency, or routine adherencerather than guaranteed fat loss

You only reduce injections when no further improvement to symptoms can be seen

The therapy works best when combined with consistent exercise, balanced nutrition, and sufficient sleep, which potentiate its anabolic and metabolic effects