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Cells expressing ms SI-TGP were disrupted using a Constant cell disruptor

& Hazell, S

20512058, Sep

Terminally on 6th week animals were sacrificed and kidneys were isolated to assess kidneys weight and markers of oxidative stress such as reduced glutathione, lipid peroxidation, and nitrite levels

These include the mitochondrial unfolded protein response (UPR mt ), the integrated stress response (ISR), mTOR signaling, and the endoplasmic reticulum unfolded protein response (UPR)

An analysis of the free energy minima and maxima for the water probe in subpockets A-C using SZMAP 37 and WaterOrientation extension in VIDA 40 is shown in Fig