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doi: 10.1016/S0021-9150(00)00739-5

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Nausea severity peaks during the titration phase (weeks 18) because amylin receptor density in the area postrema is high and initial agonism triggers emetic signalling before downregulation occurs

Lomustine and Fotemustine are other important alkylating agents used orally in the treatment of recurrent GBM that can cross the bloodbrain barrier due to small size and high lipophilicity [41,42,43]

This led researchers to conclude that epithalon may prolong the lifespan of cells and organisms [4]

Increasing evidence supports lactate-mediated lactylation as a critical modulator in neurological disorders