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In addition, let-7b-5p inhibitor can downregulate the expression of Cd36, Fatp1 , and Fabp1 (which are fatty acid transporter genes), upregulate mitochondrial genes' expression, like Cox5b and Atp5a , and reduce lipid accumulation in CL-316,243 (CL)/cold-exposed mice and HFD-induced obese mice (113)

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