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Up to 65% of cysteine is bound to proteins (protein s -cysteinylation

de Zambotti, Massimilian,o PhD

Toxicology Letters

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The causes underlying these effects remain unclear, though it is interesting to note that several enzymes involved in synthesis or metabolism of some of these amino acids are among those that have been identified as potential TRX targets through redox protemics approaches (Montrichard et al., 2009)

Many of these agents also promote oxidative stress and inflammatory responses, exacerbating cochlear damage and auditory dysfunction