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Muscle Nerve 14:12421246 Saberi S, Stauffer JE, Schulte DJ et al (2015) Neuropathology of amyotrophic lateral sclerosis and its variants

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however, zinc binding negatively affects axogenic, differentiative and prosurvival functions of PEDF by suppressing its ability to activate receptor PEDF-R/PNPLA2

The PEP can then serve as a substrate in the gluconeogenesis pathway

These stress hormones are produced and secreted by the adrenal glands and in the case of NE additionally by neurons located in the LC (brain) and the sympathetic nervous system (SNS) (periphery)

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