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Other symptoms that have been reported in adult patients with vitamin B12 deficiency include glossitis, skin hyperpigmentation, infertility, hearing loss, bone disease and macular degeneration[8]
They receive nutrients primarily through diffusion from adjacent vertebral endplates
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For longer-standing issues, the full benefit typically develops over a complete 8-week cycle
the FDA advisory committee then voted against permitting their compounding, leaving them restricted (source)
