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Open simple prostatectomy Open simple prostatectomy (OSP) surgery involves an open incision in the lower abdomen to remove the inner portion of the prostate

Most patients experience minimal discomfort during the procedure, feeling only a mild stinging or burning sensation when the solution is injected

doi: 10.1016/j.canlet.2014.11.014 20 HambrightWSFonsecaRSChenLNaRRanQ

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It is important to recognize that deficiencies in these cofactors could present in a similar manner as enzymatic deficiencies of specific pathways

In APCmin/+ mice, 4-HPR treatment decreased tumorigenesis and M2 macrophage infiltration, suggesting that inhibition of M2 polarization is a key mechanism underlying its chemopreventive effects in colon cancer (43)