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10.1016/j.biomaterials.2006.08.012 74 NelsonB.JohnsonM.WalkerM.RileyK.SimsC

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Materials and methods Animals and tissue collection Animal work was approved by the McGill Animal Care Committee and followed guidelines established by the Canadian Council on Animal Care (CCAC)

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Treatment of these NSCs with antioxidants, or the introduction of a mitochondrially-targeted OGG1 protein ameliorated mtDNA damage and rescued neurogenesis, indicating the importance of mtDNA repair to NSC fate determination [193]