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This creates an interesting mechanistic distinction

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One study on 51 patients with type 2 diabetes found that vitamin D supplementation reduced reported pain levels by almost 50% and suggested that vitamin D could be used as an analgesic in patients with pain caused by diabetic neuropathy (Lee 2008)

After TFRC binds to transferrin-carrying Fe 3+ , the transferrin-TFRC complex facilitates iron uptake via endocytosis ( Untargeted metabolomics, which encompasses a wide range of metabolites, offers advantages in identifying and relatively quantifying metabolites