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Thus, there are at least two, and possibly three ways that light from the eye can activate pain circuits: through conventional rod and cone circuits, through IPRGCs, and through melanopsin-containing ganglion-type cells outside the retina

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How to Read a Clinical Trial Registration (NCT Entry) ClinicalTrials.gov NCT entries contain structured data on study design, endpoints, eligibility, and status

Because the alternative is not a safe outcome