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biology Nicotinamide regulation Cellular signaling Enzyme function Cellular bioenergetics Methylation pathways Mechanism of Action 5-Amino-1MQ selectively inhibits the enzyme nicotinamide N-methyltransferase (NNMT), which plays a key role in nicotinamide utilization and cellular methylation pathways

Purpose: Therapeutic or diagnostic

People that have pernicious anemia usually require B12 shots

Compound Name: 5-Amino-1MQ Chemical Classification: NNMT (Nicotinamide N-Methyltransferase) Inhibitor Chemical Name: 5-Amino-1-Methylquinolinium Appearance: White to off-white lyophilised powder Solubility: Typically soluble in bacteriostatic water or sterile research-grade diluents Research Category: Metabolic- and NAD-pathway research compound Common Research Areas: NAD-metabolism investigations NNMT-pathway research Mitochondrial-function studies Metabolic-regulation investigations Glucose- and insulin-related research Healthy-aging and cellular-energy research models Cellular-maintenance and physiological-resilience investigations For Laboratory and Research Purposes Only Not intended for human consumption or therapeutic use

High-dose oral therapy (10002000 micrograms daily) can be effective in some cases of malabsorption through passive diffusion, but is not routine first-line treatment for pernicious anaemia in the UK