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Additionally, the remodeling of the extracellular matrix (ECM) facilitated by ROS enhances tumor invasion, allowing melanoma cells to disseminate more effectively 56

Overall, these results indicate that GPx4 inactivation alone is insufficient to induce hepatic ferroptosis
Another neurodegeneration condition is ataxia-telangiectasia (A-T), a disorder caused by mutations in the ataxia-telangiectasia-mutated (ATM) kinase gene
