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they tested staged escalation strategies leading to different maintenance doses

This distinction underscores the importance of viewing GLP-1RAs as systemic immunometabolic modulators with secondary effects on thyroid autoimmunity, rather than as agents with direct thyroidal targets

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It should be noted that there is a lack of research assessing the costbenefit analysis of periodic monitoring of vitamin B12 in those taking metformin, though it is a relatively inexpensive test to undertake

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