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Individual data were not available for review, but the authors noted that there were very few arrythmias at baseline in their study subjects, and no significant change in dialysis-associated arrhythmias was observed

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Elevated histone acetylation was confirmed in an additional cell line and shown to decrease through the depletion of KG or the suppression of KGDDs using knockdown or inhibition of IDH1, glutamine starvation or succinate supplementation (Fig