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doi: 10.1016/j.foodres.2019.108874 30 MortensenMSRuizJWattsJL

These limitations include cytotoxicity, immune rejection, regulatory obstacles, senescence and inflammation, and limited targeting precision [10, 58, 59]

These receptors regulate the transcription of genes involved in lipogenesis, fatty acid oxidation, and cholesterol transport

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Most studies evaluated twice daily dosing

The criteria for exclusion were as follows: rats with signs of external ear disorders (impacted earwax, tumors, external acoustic meatus edema, and hyperemia), rats with middle ear disorders (opacification, hyperemia, and bulging or perforations of the tympanic membrane), and rats without DPOAE in any of the studied frequencies (18 kHz)
