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Neuroendocrine-Metabolic Dysfunction and Sleep Disturbances in Neurodegenerative Disorders: Focus on Alzheimer s Disease and Melatonin

Bartus RT, Dean RL 3rd, Beer B, Lippa AS (1982) The cholinergic hypothesis of geriatric memory dysfunction
Test system Measured end-point Test conditions MA RES Reference Human lymphocytes chromosomal aberration 0.8 g/ml 2x/day, 4 days - + Obe et al

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

ERK1/2: extracellular signal-related kinases

N.BraskieM
