why don't i feel better after b12 injections Are Shots Safe? Royal Palm Beach Medical Group Feeling worse after B12 Injection:

Lancet 1998;352(9142):17212

Any perceived weight loss benefits typically relate to the correction of deficiency symptomssuch as fatigue and low moodwhich may indirectly improve an individual's capacity for physical activity and dietary adherence

Cobalamin riboswitches are conserved RNA structural elements that regulate the expression of vitamin B12 biosynthesis operons upon vitamin B12 binding ( 30 )

Meganeuron NT + 75 Tablet is a combination of three medicines: Pregabalin, Nortriptyline and Methylcobalamin

(1996) Effects of vitamin B12 on performance and circadian rhythm in normal subjects

A Phase 2b clinical trial (Heffernan 2007, 300 obese patients) tested 1 mg/day subcutaneously over 12 weeks with a weight loss result of ~2.8 kg vs placebo