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In aged rodents, the same pharmacology has been extended to skeletal-muscle pathology, where it preserves muscle stem cell function and mitigates sarcopenia [3]

It works by inhibiting tyrosinase, the enzyme responsible for melanin production, and shifting the skin toward producing lighter pigment

doi: 10.1007/s10517-007-0350-1 73 BandyopadhyaySLeeMSivaramanJChatterjeeC

An organization- and category-level comparison of diagnostic requirements for mental disorders in ICD-11 and DSM-5

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Notably, in adipose-derived MSCs (AD-MSCs), high concentrations of IL-1 and TNF- promote proliferation and osteogenic differentiation while concurrently inhibiting chondrogenic and adipogenic differentiation (Mohammadpour et al., 2016)