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TA was determined as: where 0.064 (mL -1 ) is the conversion factor

Many PD studies using SH-SY5Y cells were performed after establishing stable cell lines expressing exogenous synuclein

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Step 1: Conferring weights on reactions based on FVA From the FVA output, the computed flux ranges [MaxFlux - MinFlux] for every reaction in the network were used to generate an FVA reaction score (r) between 0 (low) and 1 (high)

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Peynshaert K, Soenen SJ, Manshian BB, Doak SH, Braeckmans K, De Smedt SC, Remaut K (2017) Coating of quantum dots strongly defines their effect on lysosomal health and autophagy