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Because BPC-157 hasnt been studied in human clinical trials, its long-term safety is unknown

Among the 12 genes related to hormone secretion, Vgf (nerve growth factor inducible) showed a highly significant increase in expression in GCGR-KO -cells (Log 2 FC = 1.38

J Mol Cell Cardiol (2019) 135:97108

The pancreatic effects of cagrilintide include modulation of glucagon secretion and enhancement of insulin sensitivity

Preliminary clinical data and lab work suggest advantages for fertility, uterine recovery, and ovarian support, though large trials are still sparse