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A role for glutathione transferase Omega 1 (GSTO1-1) in the glutathionylation cycle

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The expression of GPX3 reportedly declines with age ( in vitro study, the effect of GPX3 overexpression on H 2 O 2 -induced cellular senescence was not as strong as that of dexamethasone

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10.1016/j.bbrc.2016.03.052 72

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In some circumstances vitamin B-12 can cause the following side effects: Restenosis (reoccurrence of narrowing of a blood vessel) after stent placement / High blood pressure / Acne / Rash / Itchy or burning skin / Pink or red skin discoloration / Facial flushing / Urine discoloration / Numbness / Nausea / Difficulty swallowing / Diarrhoea / Increase in blood volume and red blood cells / Low potassium levels / Gout flare-up

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The peptide chelates free copper ions that could otherwise participate in pro-oxidant Fenton reactions, while simultaneously stimulating the expression of endogenous antioxidant enzymes such as superoxide dismutase, catalase, and glutathione peroxidase

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