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Atorvastatin treatment ameliorates cardiac function and remodeling induced by isoproterenol attack through mitigation of ferroptosis

Hydrogen peroxide, which is an essential factor for thyroid hormone biosynthesis, is produced in the thyroid gland by two isoform enzymes, i.e., dual oxidase 1 (DUOX1) and 2 (DUOX2), belonging to NOX family, with the most convincing experimental evidence found for DUOX2 [137,138,139]

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At 20 mg/ml concentration, a 10 mg maintenance dose is just 0.50 ml, which is exactly half a standard insulin syringe

However, pretreatment with cCPP-CeNPs dramatically suppressed ASCL4 expression and promoted the expression of GPX4 and xCT, outperforming other groups, including those treated with PEG-CeNPs or lCPP-CeNPs (Fig

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