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The mortality rate was 20.6%
This supraphysiological dose saturates the intrinsic factor pathway entirely, forcing absorption through passive diffusion mechanisms that are far less efficient but still produce serum B12 levels 200400 times above baseline within 24 hours

A more enticing model is that PGL-1 forms a higher-ordered, RNP complex with mRNA that enhances WAGO-1s biochemical activity
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