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Indeed, dietary phenolics may act as pro-oxidants in the presence of O 2 and transition metals, like iron and copper, catalyzing phenolics redox cycling and leading to ROS and phenoxyl radicals formation, with consequent damage in DNA, lipids and other biological components ( in vivo is still poorly understood, and this topic undoubtedly requires further research

Interestingly, LTF is also capable of binding directly to LRP1, TGFR2, and IGF-R1, triggering downstream metabolic alterations in osteoblasts (Tian et al., 2023)

The problem with drinking large amounts in a short timespan is that a sizable portion of the fluid is generally lost through urine in the following hour

Ceruloplasmin regulates the proper membrane distribution of ferroportin

It is important to avoid injecting lixisenatide after a meal or in case of a missed meal

ZnONPs affect zebrafish embryonic development, and AgNPs have been shown to reduce ovarian size in Drosophila [123]