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They also noticed that in the absence of HGF, TGF- (an EGFR ligand) activates c-MET when EGFR is blocked [101]
As research continues, it is essential to explore how this peptide works in the body, its role in male fertility, and how it could potentially be used to treat hormonal imbalances in the future

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Upregulation of Alternative Angiogenic Pathways The activation of compensatory pro-angiogenic pathways in response to anti-VEGF therapy is a well-established mechanism of acquired resistance in tumors (Ramadan et al., 2020)

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