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Targeting glucose metabolism has the potential to decrease the incidence and course of ALS, even though metabolic treatments for the disease receive little attention

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1957 births Living people Nobel laureates in Physiology or Medicine American Nobel laureates Jewish American scientists Jewish atheists American atheists American immunologists American geneticists Jewish biologists Scripps Research faculty University of California, San Diego alumni Pritzker School of Medicine alumni University of Texas Southwestern Medical Center alumni Rockefeller University Members of the United States National Academy of Sciences Howard Hughes Medical Investigators Members of the German National Academy of Sciences Leopoldina Members of the National Academy of Medicine Jewish Nobel laureates Jewish American medical doctors Polytechnic School alumni

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In one study using COS-7 fibroblast cells (derived from African green monkey kidney fibroblasts), the cells were exposed to blue LED light (465 nm, 1 mW/cm 2 , up to 1 h) 210 , and lipid profiles were analyzed using LCMS/MS

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Dysfunction of the somato-cognitive action network (SCAN)which is thought to control action execution 6,7 by coordinating arousal, organ physiology and whole-body motor plans with behavioural motivationis a potential contributor to the diverse clinical manifestations of PD

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Another critical enzyme of PPP, 6-phosphogluconate dehydrogenase (6PGD), is upregulated in ATC and inhibition of 6PGD is proven to disrupt the doxorubicin-resistant situations in ATC cells [95]

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