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However, HeLa cells are much more sensitive, with 2.5 nM (per million cells) of doxorubicin resulting in up to 80% GSH depletion for the same exposure time 38

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NAC severely impaired 4Ebp1 phosphorylation in intestines from Apc +/Min /Stard7 IEC mice, indicating that ROS promotes mTORC1 activation (Fig