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The treatments also improved liver histopathology, which was adversely affected by APAP, including issues like hepatocyte steatosis, cytoplasmic vacuolization, hydropic degeneration, and necrosis, alongside inflammation marked by the presence of mononuclear leukocytes and fibroblasts

B.GrootjansS.VegiN.HultnerL.HoppeP
Olechnowicz J, Tinkov A, Skalny A, Suliburska J

More importantly, it added complexity to the crosstalk between ROS and NO in response to high temperature

Curcumin-PLGA nanoparticles were fabricated using a double-emulsion solvent evaporation method after enhancing curcumin solubility through melt-crystallization, which dramatically increased curcumin solubility by 2627-fold compared to the pure compound

J.MorgensternR.ManciniJ.Ford-HutchinsonA.PerssonB
