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Targeting the TMA-producing gut microbiota and TMAO-related enzymes are expected to be an important method to reduce TMAO level following the development of research on the gut microbiota and TMAO

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In the penile microenvironment, preclinically demonstrated systemic inflammatory signals induce a series of structural and functional abnormalities that may lead to ED, including endothelial cell dysfunction, phenotypic transformation and apoptosis of cavernous smooth muscle cells (CSMCs), and inflammatory damage to penile nerves (204)

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Proper exercise can effectively improve the level of sdLDL-C in patients