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PMID: 23240940

The expression of Nrf2 is elevated by oncogenic K-Ras and B-Raf as well as overexpression of Myc, and its level is sustained in cancer cells that display hyperactivation of the PI3K/Akt signaling pathway 52,53

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8 Therapy of tendon injury 8.1 Antioxidants in tendon injury and repair Pharmacological antioxidant therapy has emerged as a promising approach for modulating oxidative stress in tendon injuries, aiming to counteract the deleterious effects of excessive ROS on tendon cells and ECM integrity

These include the increased biosynthesis short-chain fatty acids, digestive enzymes, enlarged size of intestinal villi, increased level of enterocytes, improvement of the immune function, modulation of the presence of intestinal microorganisms, and suppressing the growth of pathogenic microorganisms and microbial hemostasis in the gut, and the reduction of triglycerides and cortisol (Ortiz et al., 2013), inulin (Wang et al., 2022), GOS (Ren et al., 2020), and XOS (Wang et al., 2022)
A meta-analysis showed that compression therapy induces only a minor reduction in scar height [19], and the optimal pressure has to be defined
