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Key publications highlighting their development and use are also included

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Some of the DNA methylation calling tools developed for nanopore sequencing are: Nanopolish (5mC in CpG and GpC sites), Tombo (5mC, 6 mA, 4mC), SignalAlign (5mC - CpG, 5hmC), Guppy (5mC - CpG, 6 mA), NanoMod (5mC - CpG, 6 mA), DeepMod (5mC - CpG, 6 mA), DeepSignal (6 mA), Megalodon (5mC - CpG), mCaller (6 mA), methBERT, METEORE, DeepMP, NP-SMLR (5mC - GpC) [6, 90], NanoMod, MINES, Nanom6A [1], PoreMeth [69], NanoMethViz [26], nanodisco (for bacterial species and microbiomes) [99]

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However, the likelihood of this depends on both the amount of folic acid consumed and an individuals genetic capacity to metabolise it

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