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The pathophysiology underlying the relationship between fatigue and the regulatory phenomena exerted by vitamin D is quite complex and concerns both the phenomena linked to the reduction in oxidative stress and inflammation and neurobiological effects associated with both growth factors and neurotransmitters (Figure 1)
Flinn S, Herbert K, Graham K, et al

A critical consideration in ALS research and therapy development is the distinction between familial (fALS) and sporadic (sALS) forms

Schlechte HH, Schnorr D, Loning T, Rudolph BD, Pohrt UM, Loening SA

SARS-CoV-2 infection induces ferroptosis of sinoatrial node pacemaker cells

The second step in GSH synthesis is catalyzed by GSH synthase (GS, EC 6.3.2.3, formerly known as GSH synthetase)
