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Am J Physiol Endocrinol Metab (2012) 303:E334351

In scientific literature, NNMT is recognized as an enzyme that methylates nicotinamide (a precursor of NAD+) using S-adenosylmethionine (SAM) as the methyl donor, converting it to 1-methylnicotinamide (MNA) and potentially affecting cellular NAD+ availability

extra B12 doesnt accelerate fat metabolism beyond what the body already needs

Importantly, we did not observe sex-related differences in circulating IGF-1 levels in the studied groups, and serum IGF-1 levels significantly correlated with age (Fig