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Overall, CD4 and CD8 CAR T cells from each sub-group showed similar respective biological trends in the expression of metabolic proteins (Fig

These EVs were positive for EV markers, such as CD63 and TSG101, an integral component of the ESCRT-1 protein complex for the synthesis and secretion of EVs (Fig

Finally, the membranes were immersed in enhanced chemiluminescence reagents (Thermo Fisher Scientific) and the blots were visualized using a luminescence analyzer (Fusion Solo, Vilber Lourmat, France)

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Notably, vitamin D receptor (VDR) expression is widespread in renal tubular and vascular smooth muscle cells, and its signaling appears to exert both protective and potentially adverse effects (3, 5)
