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Their research found that an EZH2 inhibitor, which methylates H3K27, upregulated both CD38 mRNA and protein expression in KDM6A knockout cells, and restored the sensitivity of these knockout cells to daratumumabmediated NKcell cytotoxicity in vitro and in xenograft mouse models

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Todd, at the University of Cambridge, used the LLD assay to extract the anti-pernicious anemia factor from liver extracts, purify it, and name it vitamin B 12

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