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The function and interaction of metabolites were constructed using the KEGG database

The median fold change of the six interferon-stimulated genes IFI27 , IFI44L , IFIT1 , ISG15 , RSAD2 , SIGLEC1 when compared to expression in healthy control samples was used to create an interferon score for each individual [36]

2011 investigational study documented congestive heart failure signals leading to early study termination
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