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Its activity is linked to the control of fat storage, energy balance, and even the aging processes of cells

An injury that would have taken multiple months to heal, ended up healing in less than 1 month

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Bae M, Ahmed K, Yim JE

In mouse models of insulin resistance, it significantly inhibits NNMT activity in liver and muscle, reduces NAM methylation, increases intracellular NAD+, activates the SIRT1 pathway, promotes phosphorylation of insulin receptor substrate 1 (IRS1), enhances insulin signaling, improves insulin sensitivity, and increases glucose uptake and utilization

Diabetes care, 23(9), 1227-1231