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Pattern of Immune-Mediated Toxicities in Patients with Myelodysplastic Syndrome (MDS) Treated with Nivolumab and Ipilimumab

These observations suggest that nNOS plays a lesser role in mediating BOS-induced oxidative cell death

P.ZhangJ

As a powerful electron donor, it works at the frontline of antioxidant defense by: Directly neutralizing superoxide, hydroxyl, and peroxyl radicals Regenerating oxidized vitamin E, allowing it to continue its antioxidant function Supporting collagen synthesis, which is essential for wound healing and skin health Enhancing immune function through multiple mechanisms While effective, vitamin C has limitations including poor penetration into fatty tissues, rapid excretion from the body, and potential pro-oxidant effects at very high doses

In recent years, increased attentions are given to the patients diet, and the use of food supplements and functional food rich in vitamins and antioxidants plays a very important role in the treatment and prevention of neurodegenerative diseases such as Parkinsons disease (PD)