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Due to its strong bond with heme iron, CO inhibits the transport of oxygen in the blood, while interacting with cytochrome c oxygenase and cytochrome p450 it inhibits cellular respiration and promotes tissue death (66)

In addition, Li et al

TGF- can be released from different cells (immune cells or epithelial cells) as a latent complex that is deactivated and stored in the ECM

Engineered commensal bacteria reprogram intestinal cells into glucose-responsive insulin-secreting cells for the treatment of diabetes

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Quan, F., Zhang, S.-Q., Bai, Y.-X., Yao, X.-B., Li, H.-H., Yu, L., & Pan, C.-E