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Moreover, CST IV-associated bacteria secrete hydrolytic enzymes such as sialidases that degrade mucins 45 , compromising the integrity of the cervicovaginal mucosal barrier and increasing the risk of microbial translocation and ascending infections 53

Central activation of neurons This 6-year-old girl presents with early onset of secondary sexual characteristics (thelarche, pubarche) and vaginal bleeding accompanied by elevated gonadotropins and sex steroids

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[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Hall K.E., McDonald M.W., Gris K.N., Campos O.A., Noble E.G., Melling C.W