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These included previously treated and untreated patients, those with and without compensated cirrhosis, and those infected with HCV of all six genotypes.12,13 The inclusion of ribavirin did not appear to improve efficacy but was associated with a slightly increased incidence of some adverse events, including hematologic abnormalities

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according to estimates based on diagnoses made using accepted techniques, prevalence ranges between 3.5% for cow's milk and 0.51.3% for other common food allergies (eggs, nuts, cereals, fruit, fish and seafood).114,117 The prevalence of food intolerance, in contrast, is estimated at between 15% and 20%, and is particularly associated with gastrointestinal functional diseases, such as irritable bowel syndrome and functional dyspepsia.118 The subgroup of food intolerance disorders includes both common and less frequent conditions that can cause diarrhoea and other gastrointestinal manifestations, such as flatulence, abdominal distension, nausea, vomiting and abdominal and/or epigastric pain