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[DOI] [PubMed] [Google Scholar] 68.Zhuang X, Xiang X, Grizzle W, Sun D, Zhang S, Axtell RC, et al

Based on the network and flux analyses, we further examined the pyruvate dehydrogenase complex

Intraoperative high-dose dexamethasone for cardiac surgery: a randomized controlled trial

[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Cao L et al

Coles, F

Therapeutic implications: modulating nodes, not just scavenging Therapy should target network nodes and compartments, not just mop up oxidants: indiscriminate antioxidant loading can blunt adaptive signalling and leave the upstream drivers untouched, whereas node-specific, compartment-aware strategies act where the chemistry originates and where signals are decoded